Tangential Flow Filtration Systems and Pinch Valves

Tangential Flow Filtration (TFF) is a filtration technique in which a solution passes through the surface of a filter. It’s an efficient method for separation and purification of biomolecules and ideal for applications that require the filtration of small particle size solids. The use of pinch valves with peristaltic pumps, disposable tubing, and fittings minimizes sample cross-contamination while providing gentle processing for biomolecules.

Pinch valves are ideal for bioprocessing and industrial applications where sterility and washdown procedures are key to the process. These valves provide a quick change-out for tubes carrying different, incompatible media, ensuring sterility between devices. They also ensure minimum downtime, essential in life-saving medical applications.

Bimba | Acro’s robust 900-series valves offer reliability and performance, especially when working with less flexible, larger diameter tubing or higher media pressures that require stronger pinch forces. It is constructed of aluminum but is also available in Stainless Steel upon request. Models are 932, 933, 934, 935 and 936 cover tube sizes from 1/8″ O.D up to 1.625″ O.D.

Potential Applications:

  • Medical devices
  • Biopharmaceutical processing
  • Bioreactors
  • Tangential flow filtration (TFF)
  • Chromatography
  • Food and beverage
  • Filling and packaging

For additional information on pinch valves, please contact us.